北京索萊寶科技
專注于生物學試劑及試劑盒領域
服務熱線：18101056239
專注于生物學試劑及試劑盒領域
服務熱線：18101056239
產品型號：K106590P
更新時間：2022-08-15
廠商性質：生產廠家
訪 問 量 ：872
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產品分類
Anti-KRT18 Polyclonal Antibody
| 英文名稱 | Anti-KRT18 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | CK-18;CYK18;K18;PIG46;Cytokeratin-18 |
| 應用 | WB IHC |
| 稀釋比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反應 | Human Mouse Rat |
| 蛋白分子量 | 26kDa |
| Gene ID | 3875 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | Recombinant protein of human KRT18 |
| 性狀 | 液體 |
| Public Immunogen Range | Recombinant protein of human KRT18 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | P05783 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection. |
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