北京索萊寶科技
專注于生物學試劑及試劑盒領域
服務熱線：18101056239
專注于生物學試劑及試劑盒領域
服務熱線：18101056239
產品型號：K106612P
更新時間：2022-08-15
廠商性質：生產廠家
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產品分類
Anti-NR3C2 Polyclonal Antibody
| 英文名稱 | Anti-NR3C2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | MCR;MLR;MR;NR3C2VIT |
| 應用 | WB |
| 稀釋比例 | WB 1:500-2000. |
| 交叉反應 | Human Mouse |
| 蛋白分子量 | 107kDa |
| Gene ID | 4306 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | A synthetic peptide of human NR3C2 |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide of human NR3C2 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | P08235 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. |
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