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產(chǎn)品中心抗體Polyclonal AntibodyK106634PAnti-PGH2 Polyclonal Antibody
產(chǎn)品型號(hào)：K106634P
更新時(shí)間：2022-08-15
廠商性質(zhì)：生產(chǎn)廠家
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產(chǎn)品分類
Anti-PGH2 Polyclonal Antibody
| 英文名稱 | Anti-PGH2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | PTGS2;COX2;PHS II;PGHS-2 |
| 應(yīng)用 | IHC |
| 稀釋比例 | IHC 1:50-200. |
| 交叉反應(yīng) | Human |
| 蛋白分子量 | 69kDa |
| Gene ID | 5743 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲(chǔ)存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | A synthetic peptide of human PGH2 |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide of human PGH2 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P35354 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis. |
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